Catalog Description
Chromosomes and genes, Mendelian inheritance, Modification of Mendelian inheritance, gene interaction, inheritance and environment, Sex determination. Sex linkage, sex-limited and sex-influenced characters, linkage and crossing-over, chromosome mapping, mutation, cytoplasmic inheritance and quantitative inheritance.
Topics will be deeply discussed in a student-centered manner using digitally- enriched activities: Genetic engineering, cancer genetics, Next Generation Sequencing (NGS) techniques, applications in human molecular genetics, OMICs analysis, in silico tools for Big Data integration, CRISPR-Cas technology and genome editing.
Course Objectives
- Explain the different concepts of genetics in both prokaryotes and eukaryotes.
- Determine how gene expression regulates protein production.
- Create novel hypothesis on how our genome can contribute to solving real-life problems
Course Learning Outcomes
- Identify cellular components and explain their structure, function, the modes of cells division and gametes formation.
- Examine Mendelian patterns of inheritance and exception to the Mendelian models.
- Discover novel genes by using Linkage disequilibrium; explain the main actors involved in the DNA replication, RNA translation and the regulation of gene expression.
- Analyse transcription and the rules for protein production by categorizing the different molecular actors involved in the regulation of protein production.
- Assess the impact of genetic variations and give them the correct meaning in terms of impact on the phenotype.
- Create and organize oral and written reports on laboratory experiments and real-life situations; formulate hypothesis on the role of genetic factors in complex and multifactorial traits