Publications

  • Osorio Lopes Abath Neto, Livija Medne, Sandra Donkervoort, Maria Elena Rodríguez- García, Ying Hu, Eleonora Guadagnin, A. Reghan Foley, John F. Brandsema, Allan M. Glanzman, Gihan I. Tennekoon, Mariarita Santi, Justin H. Berger, Lynn A. Megeney, Hirofumi Komaki, Michio Inoue, Francisco Javier Cotrina-Vinagre, Aurelio Hernández- Lain, Elena Martin-Hernández, Linford Williams, Sabine Borell, David Schorling, Kimberly Lin, Konstantinos Kolokotronis, Uta Lichter-Konecki, Janbernd Kirschner, Ichizo Nishino, Brenda Banwell, Francisco Martínez-Azorín, Patrick G. Burgon*, Carsten G. Bönnemann*. (2021) MLIP causes recessive myopathy with rhabdomyolysis, myalgia and baseline high serum creatine kinase. Brain 2021 Sep 28;awab275. doi: 10.1093/brain/awab275. Online ahead of print.
  • Ahmady E, Rabaa S, Blais A, Burgon PG* (2021) Muscle enriched Lamin Interacting Protein (MLIP) is required for C2C12 myoblast differentiation. Cells 2021 Mar 10;10(3):615.
  • Patrick G. Burgon*, Marie-Elodie Cattin , Shelley A. Deeke , Elmira Ahmady. (2020) Intricate tissue-specific pattern of alternative splicing of MLIP determines MLIP’s tissue-specific functions. Journal of Integrated OMICS (in Press).
  • Weldrick JJ, Abdul-Ghani M, Megeney LA and Burgon PG*. (2019). Rapid and efficient method for the isolation of perinatal cardiomyocytes. Can J Physiol Pharmacol. 2018 May;96(5):535-539.
  • Zakariyah AF, Rajgara RF, Shelton M, Blais A, Skerjanc IS, Burgon PG* (2019) Combinatorial Utilization of Murine Embryonic Stem Cells and In vivo Models to Study Human Congenital Heart Disease. Curr Protoc Stem Cell Biol. 2019 Feb;48(1):e75.
  • Cattin ME, Deeke SA, Dick SA, Verret-Borsos ZJA, Tennakoon G, Gupta R, Mak E, Roeske CL, Weldrick JJ, Megeney LA, Burgon PG*. (2018) Expression of murine muscle-enriched A-type lamin-interacting protein (MLIP) is regulated by tissue-specific alternative transcription start sites. J Biol Chem. 2018 Dec 21;293(51):19761-19770.
  • Putinski C, Abdul-Ghani M, Brunette S, Burgon PG, Megeney LA (2018) Caspase cleavage of gelsolin is an inductive cue for pathologic cardiac hypertrophy. J Am Heart Assoc. 2018 Dec 4;7(23):e010404.
  • Lee HW, Ahmad M, Wang H-W, Weldrick JJ, Burgon PG and Leenen FHH (2018) Effects of exercise training and TrkB blockade on cardiac function and BDNF-TrkB signaling post myocardial infarction in rats. Am J Physiol Heart Circ Physiol. 2018 Oct 12.
  • Burgon, PG* and Megeney, LA*. (2018). Caspase signaling, a conserved inductive cue for metazoan cell differentiation. Semin Cell Dev Biol. 2018 Oct;82:96-104.
  • Zakariyah AF, Rajgara RF, Horner E, Cattin ME, Blais A, Skerjanc IS*, Burgon PG* (2018) In vitro modeling of congenital heart defects associated with an NKX2.5 mutation revealed a dysregulation in BMP/Notch-mediated signaling. Stem Cells. 2018 Apr;36(4):514-526.
  • Abdul-Ghani, M., Suen, C., Jiang, B., Deng, Y., Weldrick, J.J., Putinski, C., Brunette, S., Fernando, P., Lee, T.T., Flynn, P., Leenen, F., Burgon, P.G., Stewart, D.J. and Megeney, L.A. (2017) Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart. Cell Res. 2017 Oct;27(10):1195-1215.
  • Zakariyah, AF, Rajgara RF, Veinot JP, Skerjanc IS*, Burgon PG* (2017) Congenital Heart Defect Causing Mutation in Nkx2.5 Displays In vivo Functional Deficit. J Mol Cell Cardiol. 2017; 105:89-98.
  • Cattin ME, Wang J, Roeske CL, Mak E, Thorn SL, DaSilva JN, Wang Y, Lusis AJ and Burgon PG*. (2015) Deletion of MLIP (Muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/Mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation. J Biol Chem. 2015 Oct 30;290(44):26699-714.
  • Burgon PG#, Jiang J#, Wakimoto H, Onoue K, O’Meara C, Fomovsky G, McConnell BK, Lee RT, Seidman JG and Seidman CE. (2015) Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9046-51. #equal contribution
  • Zhang Y, Kuraitis D, Burgon PG, Crowe S, Vulesevic B, Beanlands RS, deKemp RA, DaSilva JN, Ruel M, Suuronen EJ. (2015) Development of reporter gene imaging techniques for long-term assessment of human circulating angiogenic cells. Biomed Mater. 2015 Mar 18;10(3):034104.
  • Burgon, PG*, (2012) Human genome organization-symbolized muscle-enriched a-type lamin-interacting protein to clear up confusion. Circ Res. 2012 Oct 12;111(9):e252.
  • Ahmady E, Deeke SA, Rabaa S, Kouri L, Kenney L, Stewart AF, Burgon PG*. (2011) Identification of a novel muscle enriched A-type lamin interacting protein (MLIP). J Biol Chem. 2011 Jun 3;286(22):19702-13.
  • Teng AC, Kuraitis D, Deeke SA, Ahmadi A, Dugan SG, Cheng BL, Crowson MG, Burgon PG, Suuronen EJ, Chen HH, Stewart AF. (2010) IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression. FASEB J. 2010 Dec;24(12):4825-34.
  • Ogawa T, Forero M, Burgon PG, Kuroski de Bold ML, Georgalis T, de Bold AJ. (2009) Role of potassium channels in stretch-promoted atrial natriuretic factor secretion. J Am Soc Hypertens. 2009 Jan-Feb;3(1):9-18.
  • King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA. (2008) E2F3 plays an essential role in cardiac development and function. Cell Cycle. 2008 Dec 22;7(23).
  • Wolf CM, Pizard A, Burgon PG, Ahmad F, Sherwood M, Branco DM, Fishman GI, Stewart CL, Seidman CE, Seidman JG, Berul CI. (2008) A Mouse Model for Cardiac Conduction System Disease in Laminopathies. J Mol Cell Cardiol. 2008 Feb;44(2):293-303.
  • Pizard A, Burgon PG, Paul DL, Bruneau BG, Seidman CE, Seidman JG. (2005) Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum. Molecular and Cellular Biology. 2005 Jun;25(12):5073-83.
  • Palmer BM, Noguchi T, Wang Y, Heim JR, Alpert NR, Burgon PG, Seidman CE, Seidman JG, Maughan DW, LeWinter MM. (2004) Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium. Circ Res. 2004 Jun 25;94(12):1615-22.
  • Palmer BM, Georgakopoulos D, Janssen PM, Wang Y, Alpert NR, Belardi DF, Harris SP, Moss RL, Burgon PG, Seidman CE, Seidman JG, Maughan DW, Kass DA. The role of cardiac myosin binding protein C in maintaining left ventricular systolic elastance. Circ Res. 2004; 94: 1249-55.
  • Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG. (2003) Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White Syndrome in glycogen storage cardiomyopathy. Circulation 2003; 107 (22): 2850-6.
  • Burgon PG*, Lee WL, Nixon AB, Peralta EG, Casey PJ. (2001) Phosphorylation and nuclear translocation of a Regulator of G-protein Signaling (RGS10). J Biol Chem. 2001; 276 (35): 32828-34.
  • Burgon PG, Stanton PG, Pettersson K, Robertson DM. (1997) Effect of desialylation of highly purified human LH isoforms on their in vitro bioactivity, radioreceptor activity and immunoactivity.  Reproduction, Fertility and Development 1997; 9: 501-508.
  • Burgon PG, Stanton PG, Robertson DM. (1996) In vivo bioactivities and clearance patterns of highly purified hLH isoforms.  Endocrinology 1996; 137: 827-836.
  • Stanton PG, Burgon PG, Hearn MTW, Robertson DM. (1996) Structural and functional characterization of hFSH and hLH isoforms. Molecular and Cellular Endocrinology 1996; 125: 133-141.
  • Stanton PG, Zhiping S, Kecorius E, Burgon PG, Robertson DM, Hearn MTW. (1995) Application of a sensitive HPLC-based fluorometric assay to determine the sialic acid content of human gonadotropin isoforms.  Journal of Biochemical and Biophysical Methods 1995; 30: 37-48.
  • Burgon PG, Robertson DM, Stanton PG, Hearn MTW. Immunological activities of highly purified isoforms of human follicle stimulating hormone correlates with in vitro bioactivities. Journal of Endocrinology 1993; 139: 511-518.
  • Stanton PG, Pozvek G, Burgon PG, Robertson DM, Hearn MTW. (1993) Isolation and characterization of human luteinizing hormone isoforms. Journal of Endocrinology 1993; 138: 529-543.
  • Stanton PG, Robertson DM, Burgon PG, Schmauk-White B, Hearn MTW. (1992) Isolation and physiochemical characterization of human follicle-stimulating hormone isoforms. Endocrinology 1992; 130: 2820-2832.

Book Chapters

  • Lisa Lin, Tiffany Barszczewski, Patrick G. Burgon*, Glen F. Tibbits* (2021) Chapter 30 Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as a platform for modeling arrhythmias. In: Stem cells: From Theory to Practice. Springer Nature (In Accepted and In press)
  • Stanton PG, Robertson DM, Burgon PG, Schmauk-White B, Hearn MTW. (1991) Purification and biological activities of isoforms of human FSH.  In: Hunzicker-Dunn M, Schwartz N (eds), Regulation and Actions of FSH. New York: Springler-Verlag, 1991, pp. 339-344.