Alaaldin M. Alkilany

Alaaldin M. Alkilany

Professor of Pharmaceutics and Nanotechnology/Research Coordinator at the College of Pharmacy

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Publications

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Publications:

  1. Gold nanorods as nanoadmicelles: 1-naphthol partitioning into a nanorod-bound surfactant bilayer. Langmuir. 2008
  2. Cation exchange on the surface of gold nanorods with a polymerizable surfactant: Polymerization, stability, and toxicity evaluation. Langmuir. 2009
  3. Gold nanoparticles with a polymerizable surfactant bilayer: Synthesis, polymerization, and stability evaluation. Langmuir. 2009
  4. Chemical sensing and imaging with metallic nanorods. Chem. Commun. 2010
  5. Cellular uptake and cytotoxicity of gold nanorods: Molecular origin of cytotoxicity and surface effects. Small. 2010
  6. Polyelectrolyte coating provides a facile route to suspend gold nanorods in polar organic solvents and hydrophobic polymers. ACS Appl. Mater. Interfaces. 2010
  7. Toxicity and cellular uptake of gold nanoparticles: What we have learned so far? J. Nanopart. Res. 2010
  8. Gold nanoparticles in biology: Beyond toxicity to cellular imaging. Acc. Chem. Res. 2010
  9. Clickable polyglycerol hyperbranched polymers and their application to gold nanoparticles and acid-labile nanocarriers. Chem. Commun. 2011
  10. Gold nanorod crystal growth: From seed-mediated synthesis to nanoscale sculpting. Curr. Opin. Colloid Interface Sci. 2011
  11. Gold nanorods: Their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions. Adv. Drug Deliv. Rev. 2012
  12. The golden age: Gold nanoparticles for biomedicine. Chem. Soc. Rev. 2012
  13. Toxicity and cellular uptake of gold nanorods in vascular endothelium and smooth muscles of isolated rat blood vessel: Importance of surface modification. Small. 2012
  14. Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway. Br. J. Pharmacol. 2012
  15. Nanoparticle-protein interactions: A thermodynamic and kinetic study of the adsorption of bovine serum albumin to gold nanoparticle surfaces. Langmuir. 2013
  16. Exocytosis of nanoparticles from cells: Role in cellular retention and toxicity. Adv. Colloid Interface Sci. 2013
  17. The gold standard: Gold nanoparticle libraries to understand the nano-bio interface. Acc. Chem. Res. 2013
  18. Gold nanorods as nanoadmicelles: 1-naphthol partitioning into a nanorod-bound surfactant bilayer. Langmuir. 2014
  19. Facile phase transfer of gold nanoparticles from aqueous solution to organic solvents with thiolated poly(ethylene glycol). RSC Adv. 2014
  20. Colloidal stability of citrate and mercaptoacetic acid capped gold nanoparticles upon lyophilization: Effect of capping ligand attachment and type of cryoprotectants. Langmuir. 2014
  21. Homing peptide-conjugated gold nanorods: The effect of amino acid sequence display on nanorod uptake and cellular proliferation. Bioconjug. Chem. 2014
  22. Synthesis of monodispersed gold nanoparticles with exceptional colloidal stability with grafted polyethylene glycol-g-polyvinyl alcohol. J. Nanomater. 2015
  23. Nanotoxicology: Advances and pitfalls in research methodology. Nanomedicine. 2015
  24. Misinterpretation in Nanotoxicology: A Personal Perspective. Chem. Res. Toxicol. 2016
  25. Gold nanoparticles for biomedical imaging and their biological response. New Developments in Gold Nanomaterials Research. 2016
  26. Protein corona: Opportunities and challenges. Int. J. Biochem. Cell Biol. 2016
  27. High conversion of HAuCl4 into gold nanorods: A re-seeding approach. J. Colloid Interface Sci. 2016
  28. Phase transfer of citrate stabilized gold nanoparticles using nonspecifically adsorbed polymers. J. Colloid Interface Sci. 2016
  29. Colloidal stability of gold nanorod solution upon exposure to excised human skin: Effect of surface chemistry and protein adsorption. Int. J. Biochem. Cell Biol. 2016
  30. Preparation of Aqueous Core-Poly(D,L-Lactide-co-Glycolide) Shell Microcapsules Containing Mononuclear Cores by Internal Phase Separation: Optimization of Formulation Parameters. J. Pharm. Sci. 2017
  31. Antibacterial activity of gold nanorods against Staphylococcus aureus and Propionibacterium acnes: Misinterpretations and artifacts. Int. J. Nanomedicine. 2017
  32. Selected standard protocols for the synthesis, phase transfer, and characterization of inorganic colloidal nanoparticles. Chem. Mater. 2017
  33. Introducing Students to Surface Modification and Phase Transfer of Nanoparticles with a Laboratory Experiment. J. Chem. Educ. 2017
  34. Cellular uptake of nanoparticles: Journey inside the cell. Chem. Soc. Rev. 2017
  35. Freeze-drying of monoclonal antibody-conjugated gold nanorods: Colloidal stability and biological activity. Int. J. Pharm. 2018
  36. Preferential accumulation of gold nanorods into human skin hair follicles: Effect of nanoparticle surface chemistry. J. Colloid Interface Sci. 2018
  37. The taste of commercially available clarithromycin oral pharmaceutical suspensions in the Palestinian market: Electronic tongue and in vivo evaluation. Sensors. 2018
  38. Simple Experiment to Determine Surfactant Critical Micelle Concentrations Using Contact-Angle Measurements. J. Chem. Educ. 2018
  39. Synchrotron-based X-ray fluorescence study of gold nanorods and skin elements distribution into excised human skin layers. Colloids Surf. B Biointerfaces. 2018
  40. Nano-Photothermal ablation effect of Hydrophilic and Hydrophobic Functionalized Gold Nanorods on Staphylococcus aureus and Propionibacterium acnes. Sci. Rep. 2018
  41. Synthesis of gold nanoparticles using leaf extract of ziziphus zizyphus and their antimicrobial activity. Nanomaterials. 2018
  42. Ligand density on nanoparticles: A parameter with critical impact on nanomedicine. Adv. Drug Deliv. Rev. 2019
  43. Synergistic antibacterial activity of silver nanoparticles and hydrogen peroxide. PLoS ONE. 2019
  44. Formulation and characterization of combretastatin A4 loaded PLGA nanoparticles. Mater. Res. Express. 2019
  45. Tunable sustained release drug delivery system based on mononuclear aqueous core-polymer shell microcapsules. Int. J. Pharm. 2019
  46. Facile Functionalization of Gold Nanoparticles with PLGA Polymer Brushes and Efficient Encapsulation into PLGA Nanoparticles: Toward Spatially Precise Bioimaging of Polymeric Nanoparticles. Part. Part. Syst. Charact. 2019
  47. Identification of substandard drug products using electronic tongue: Cefdinir suspension as a pilot example. Drug Des. Dev. Ther. 2019
  48. The role of ligands in the chemical synthesis and applications of inorganic nanoparticles. Chem. Rev. 2019
  49. Facile Hydrophobication of Glutathione-Protected Gold Nanoclusters and Encapsulation into Poly(lactide-co-glycolide) Nanocarriers. Sci. Rep. 2019
  50. Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth. Int. J. Pharm. 2020
  51. Synthesis of Fluorescent Silver Nanoclusters: Introducing Bottom-Up and Top-Down Approaches to Nanochemistry in a Single Laboratory Class. J. Chem. Educ. 2020
  52. Silver nanoparticles, a promising treatment against clinically important fluconazole-resistant Candida glabrata. Lett. Appl. Microbiol. 2021
  53. Evaluation of the Benefits of Microfluidic-Assisted Preparation of Polymeric Nanoparticles for DNA Delivery. Mater. Sci. Eng. C. 2021
  54. Quercetin-gold nanorods incorporated into nanofibers: development, optimization and cytotoxicity. RSC Adv. 2021
  55. Correction to Selected Standard Protocols for the Synthesis, Phase Transfer, and Characterization of Inorganic Colloidal Nanoparticles. Chem. Mater. 2021
  56. PLGA-Gold Nanocomposite: Preparation and Biomedical Applications. Pharmaceutics. 2022
  57. Therapeutic outcomes and biodistribution of gold nanoparticles in collagen-induced arthritis animal model. J. Drug Deliv. Sci. Technol. 2022
  58. Following drug degradation and consequent taste deterioration of an oral reconstituted paediatric suspension during dosing interval via electronic tongue. Saudi Pharm. J. 2022
  59. Editorial: Anti-cancer drug delivery: lipid-based nanoparticles. Front. Oncol. 2023
  60. Unlocking the Therapeutic Potential of BCL-2 Associated Protein Family: Exploring BCL-2 Inhibitors in Cancer Therapy. Biomol. Ther. 2023
  61. Quality by Design Approach in Liposomal Formulations: Robust Product Development. Molecules. 2023
  62. Can we use normal saline stored under stress conditions? A simulated prehospital emergency medical setting. Heliyon. 2023
  63. Comprehensive evaluation of the pharmacological and toxicological effects of γ-valerolactone as compared to γ-hydroxybutyric acid: Insights from in vivo and in silico models. Drug Alcohol Depend. 2023
  64. A Novel Laboratory Session to Demonstrate Interfacial Phenomena and Spreading Coefficient Using Consumer Products. J. Chem. Educ. 2023
  65. QbD Approach for the Development of a Nano-Liposomal Hydrogel of Cannabidiol for Topical Management of Skin Disorders. J. Drug Deliv. Sci. Technol. 2023
  66. Eutectics in Pharmacy Curriculum: A Simple Demonstration with Pharmaceutical Relevance. J. Chem. Educ. 2023
  67. Investigating Strategies to Enhance the Aqueous Solubility of Ketamine HCl for Intranasal Delivery. Pharmaceutics. 2024
  68. Doxorubicin conjugates: a practical approach for its cardiotoxicity alleviation. Expert Opin. Drug Deliv. 2024
  69. Formulation optimization of lyophilized aptamer-gold nanoparticles: Maintained colloidal stability and cellular uptake. Heliyon. 2024
  70. The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports. NeuroToxicology. 2024
  71. Dual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer. Expert Opin. Drug Deliv. 2024
  72. Utilization of the Transparent Peer Review Policy to Train Graduate Pharmacy Students on Scientific Critique. Am. J. Pharm. Educ. 2024
  73. Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence. Psychopharmacology. 2024
  74. Inhalable Nanotechnology-Based Drug Delivery Systems for the Treatment of Inflammatory Lung Diseases. Pharmaceutics. 2025
  75. Time-based tracking of temperature and humidity of emergency medical service rapid response vehicles in Qatar: a prospective observational study. BMC Emerg. Med. 2025
  76. Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters. Curr. Drug Deliv. 2025
  77. Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels. Emergent Mater. 2025